SABnzbd Forums

Add feature that allows the use of different Network adapter or internet connection ,
for example to use Wireless connection or to use Ethernet connection , when both are turned on.

Similar to a feature found in qBittorrent from which you can choose different adaptor for downloads... Advanced > Network Interface

This has been discussed before, and: too niche, too risky for normal users.

But, AFAIK, SAB supports traffic via an outbound proxy, so you can bind that proxy to an interface, and use that proxy.
Or, let the OS take care of the routing.